The purpose of this clinical trial is to learn whether ozonated water and hypochlorous acid solution can restore the integrity of the oral mucosa. In addition, the investigators will learn about the safety of ozonated water and hypochlorous acid solution. The main questions that participants need to answer are:
What medical conditions do participants have while taking ozonated water and hypochlorous acid solution?
Investigators will compare ozonated water and hypochlorous acid solution with 0.12% chlorhexidine gluconate solution to see if it helps to restore the integrity of the oral mucosa.
Participants:
Participants will be asked to agree to receive oral care 4 times a day, every day for 1 week.
Be between the ages of 18-65,
Have been on mechanical ventilation for at least 24 hours,
Have no intolerance or allergy to the solutions,
Agree to participate in the study
Having a contraindication for oral care
Not agreeing to participate in the study
Parallel
Control 1
DrugResearchers will perform oral care with ozonated water and hypochlorous acid solution to restore oral mucous membrane integrity.
oral assessment guide
The Oral Assessment Scale will be used to assess patients' oral mucosa before oral care is provided. his scale has sections on the lips, mucosa, tongue, teeth and saliva. Each section is scored from1 to 4, and the total score is between 5 and 20. A score of 5 is assessed as normal oral mucosa, 6-10 as slight dysfunction, 11-15 as moderate dysfunction and 16-20 as severe dysfunction.
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This trial is not recruiting at the moment. You can still explore other options:
