Efficacy and Safety of Adding Dexmedetomidine to Levobupivacaine in Rectus Sheath Block Compared to Quadratus Lumborum Block in Patients Undergoing Lower Abdominal Cancer Surgery: A Randomized Clinical Trial

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorAssiut University

About this trial

Surgical trauma activates numerous receptors leading to severe postoperative pain. Seventy to seventy-five percent of the pain is somatic, originating from the anterior abdominal wall, and it often persists for 72 hours after open surgery. The objective of this study is to compare the efficacy and safety of adding dexmedetomidine to Levobupivacaine in rectus sheath block with quadrates lumborum block in patients undergoing lower abdominal cancer surgeries.

Eligibility criteria

Qualifiers

Patients subjected to major lower abdominal cancer surgeries.

The enrolled age will be from 18 years to 70 years

ASA I-III and NYHA I-III.

Disqualifiers

ASA physical status >III and NYHA>III

Patient refusal

Body mass index >40 kg/m2

Preoperative opioid consumption

Trial design

Treatments tested in this trial

  • Levobupivacaine
  • Levobupivacaine + Dexmedetomidine

Treatment groups

122 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators