About this trial
This study wants to understand if using a pre-operative anesthetic injection could contribute to better pain relief after the surgery. This injection is referred to as an erector spinae plane block (ESPB, or "Block" for short). In the past, blocks have been commonly used to alleviate different types of pain, including pain following lumbar spine surgery, but our investigators are curious to study if adding two additional commonly used drugs could improve pain relief following surgery when used together. This possibility for improvement in pain management is important for our doctors to study because they want to find ways to reduce the amount of pain medication required after surgery.
We try to assess if one treatment is better than the other by looking into the amount of pain medication used immediately after the surgery (up to five times within the first 2 days; this is usually done by reviewing progress notes) and by asking patients if they can share with us their pain experienced at different times during their stay at the hospital and at 2-weeks after their procedure.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Medically optimized patients undergoing 1-3 level lumbar fusion surgery for treatment of degenerative lumbar spinal pathologies
Aged 18 years or older
English-speaking patients
Disqualifiers
Patients with surgical indications for infection, malignancy, or trauma
women who are pregnancy or breastfeeding
Patients with respiratory compromise
Patients who are smokers
Trial design
Parallel
Treatments tested in this trial
Adjuvant analgesia
DrugPatients will receive adjuvant dexmedetomidine (25mcg) and dexamethasone (5mg) in addition to bupivacaine.
Control (Standard treatment)
DrugPatient will receive standard ESPB with bupivacaine and normal saline
Treatment groups
Trial outcomes
Primary outcomes
Postoperative opioid consumption
measured in morphine milligram equivalents (MME)
Locations
Sponsors and contacts
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This trial is not recruiting at the moment. You can still explore other options: