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Fibrinogen Concentrates Versus Cryoprecipitate in Liver Transplant Surgery

ConditionLiver Diseases
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age20-75
SponsorKonkuk University Medical Center

About this trial

We compared the time consumed for goal-directed management of hypofibrinogemia using two strategies during liver transplant (LT) surgery: a conventional cryoprecipitate-based strategy versus a lyophilized fibrinogen concentrate-based strategy

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Liver disease undergoing Liver transplantation

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • fresh frozen plasma

    Biological/Vaccine

    transfusion of fresh frozen plasma

  • prothrombin complex concentrate

    Biological/Vaccine

    prothrombin complex concentrate administration

Treatment groups

92 Participants
are divided into 2 treatment groups
Group A: cryoprecipitateActive comparator 1 intervention
Group B: fibirnogen concentrateExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

intergroup difference in the treatment time (T-time)

The treatment time (T-time): the duration from ordering cryoprecipitate or FC to completing its administration

Time frame
1 min

Secondary outcomes

1

Red Blood Cell amount

Red Blood Cell transfusion amount during surgery

Time frame
1 hour
2

FFP amount

FFP transfusion amount during surgery

Time frame
1 hour
3

Platelet amount

Platelet transfusion amount during surgery

Time frame
1 hour
4

r-time

CK r-time after PCC or FFP

Time frame
1 min

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Konkuk University Medical Center

Lead sponsor

Samsung Medical Center

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: