About this trial
High levels of Testosterone causes high amounts of skin bacteria (Cutibacterium Acnes) which can go into the skin during a shoulder replacement surgery and cause a terrible infection.
The goal of this experiment is to have participants take Finasteride, a medication that blocks testosterone production, for 2 weeks and evaluate the following:
* Blood levels of testosterone * Amount of bacteria on the skin.
Participants will:
* Be assigned to take Finasteride, or a placebo (a look-alike pill with no active medicine) once daily, for 2 weeks * Have a small sample of their blood collected and their skin swabbed with a Q-tip to determine Testosterone levels and bacteria on the skin * Blood draw and skin testing will take place before starting Finasteride or the placebo (day 0) and at the end of the experiment (day 14).
Eligibility criteria
Qualifiers
Adult males
Age between 18 and 65 Exclusion
History of cryptorchidism, hypospadias, or other congenital abnormality of male reproductive tract
Female sex
Disqualifiers
None
Trial design
Treatments tested in this trial
- Finasteride 1 mg
- Placebo Control