Finasteride and Cutibacterium

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexMale
Age18-65
SponsorUniversity of Washington

About this trial

High levels of Testosterone causes high amounts of skin bacteria (Cutibacterium Acnes) which can go into the skin during a shoulder replacement surgery and cause a terrible infection.

The goal of this experiment is to have participants take Finasteride, a medication that blocks testosterone production, for 2 weeks and evaluate the following:

* Blood levels of testosterone * Amount of bacteria on the skin.

Participants will:

* Be assigned to take Finasteride, or a placebo (a look-alike pill with no active medicine) once daily, for 2 weeks * Have a small sample of their blood collected and their skin swabbed with a Q-tip to determine Testosterone levels and bacteria on the skin * Blood draw and skin testing will take place before starting Finasteride or the placebo (day 0) and at the end of the experiment (day 14).

Eligibility criteria

Qualifiers

Adult males

Age between 18 and 65 Exclusion

History of cryptorchidism, hypospadias, or other congenital abnormality of male reproductive tract

Female sex

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Finasteride 1 mg
  • Placebo Control

Treatment groups

40 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators