Letermovir for R+ Study

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Wisconsin, Madison

About this trial

The purpose of this clinical trial is to find out whether a medication, called letermovir, can help prevent a virus called cytomegalovirus (CMV) in participants who receive a kidney or liver transplant and who have already been exposed the CMV.

Participants will take letermovir for 84 days.

Eligibility criteria

Qualifiers

Adults who are at moderate risk for CMV after transplant (CMV IGG+, including D+/R+ or D-/R+)

Adults who received a kidney transplant, liver transplant, or any combination thereof

Disqualifiers

Known contraindication to letermovir or its excipients

Current participation in another CMV related study

Unwilling or unable to participate in the study protocol

Trial design

Treatments tested in this trial

  • Letermovir

Treatment groups

146 Participants
are divided into 1 treatment group

Sponsors and collaborators

University of Wisconsin, Madison

Lead sponsor

Merck Sharp & Dohme LLC

Collaborator