Low-Dose Ketamine Infusion During Burn Wound Care
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Tennessee
About this trial
The current standard of care (SOC) (i.e. fentanyl and midazolam) offers limited efficacy for preventing or relieving pain. Ketamine infusions may provide the benefits of analgesia, minimize adverse events, and reduce opioid use. The purpose of this study is to determine if adding a low dose ketamine infusion during wound care will safely provide pain relief for patients with burn injury.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Admitted to burn service with thermal injury
Disqualifiers
unable/unwilling to consent within 72 hours
unable to report NRS
known contraindication to ketamine
< than 18 years of age
Trial design
Design model
Parallel
Treatments tested in this trial
Ketamine
DrugInfusion during wound care
0.9% NaCl
DrugInfusion during wound care
Treatment groups
140 Participants
are divided into 2 treatment groupsGroup A: KetamineExperimental treatment 1 intervention
Group B: PlaceboPlacebo comparator 1 intervention
Trial outcomes
Primary outcomes
1
Analgesia
Numeric Pain Rating Scale (0 - 10, with 0 being absence of pain and 10 being the worst pain imaginable)
Time frame
up to 7 days from enrollmentSponsors and contacts
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Source ClinicalTrials.gov