Women requiring epidural labor analgesia were randomized into two groups, one with the local anesthetic chloroprocaine and the other with ropivacaine. The primary outcome was to observe the analgesic scores of the two groups of drugs as well as adverse reactions.
Primigravid women with full-term pregnancies scheduled for labor analgesia
Determination of labor onset to cervical dilatation ≤ 5cm;
Visual analogue scale (VAS) pain score during contractions >50 mm (0 mm = no pain at all, 100 mm = most intense pain);
Age ≥20 years;
Twin or multiple pregnancies
Hypertension
Severe cardiopulmonary and hepatic or renal disease
Severe pregnancy comorbidities such as preeclampsia, eclampsia, HELLP syndrome, placenta praevia, placental abruption, etc.
Women's Hospital School Of Medicine Zhejiang University
Lead sponsor
Beijing Obstetrics and Gynecology Hospital
Collaborator
International Peace Maternity and Child Health Hospital
Collaborator
Nanjing Medical University
Collaborator
Anhui Women and Children's Medical Center
Collaborator
Jiaxing Maternity and Child Health Care Hospital
Collaborator
Gansu Maternal and Child Health Center
Collaborator
Urumqi Maternal and Child Health Center
Collaborator
Shengjing Hospital
Collaborator
Zhongnan Hospital
Collaborator
Second Affiliated Hospital of Wenzhou Medical University
Collaborator
Second Hospital of Jilin University
Collaborator