About this trial
The purpose of this study is to develop a multi-modal protocol for pain management after TURP that minimizes opioid use. The investigators hypothesize this approach will provide non-inferior pain control to the current standard of care which includes opioids as the primary agent. The investigators believe this is an important step in reducing the opioid epidemic in surgical patients.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Are identified as candidates for TURP
Are 18 years of age or greater
Are proficient in English
Disqualifiers
Have filled an opioid prescription in the last 2 months
Have an allergy to a medication included in the protocol
Have a history of pelvic radiation
Have renal failure (Serum Cr > 2.0 mg/dl), peptic ulcer disease, history of gastric bypass, cirrhosis, or other contraindication precluding use of NSAID's
Trial design
Parallel
Treatments tested in this trial
Ibuprofen 600 mg
DrugWe'll be adding ibuprofen while trying to limit oxycodone use while hospitalized. Patients will not be discharged with a narcotic.
Education
BehavioralWe'll be adding education to patient's post-operative instructions to aid in their pain control management.
Treatment groups
Trial outcomes
Primary outcomes
Opioid Consumption
Total opioid utilization
Pain Scores
Numerical Rating Scale Pain Scores (Range: 0-10, where 0 is no pain and 10 is the worst pain)
Secondary outcomes
Presence of a foley catheter at discharge.
Was the patient discharged with a Foley catheter?
Presence of narcotic side effects
nausea/vomiting, pruritus, constipation, dizziness or feelings of sedation
Were there any post-operative complications
Any complications post-operatively that occurred in the immediate post-operative setting.
Sponsors and contacts
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Benaroya Research Institute
Lead sponsor
Virginia Mason Hospital/Medical Center
Collaborator