Oral Methadone in Cardiac Surgery
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorMayo Clinic
The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anesthesia on postoperative pain for patients undergoing elective cardiac surgery.
None
Chronic pain requiring opioid medications as an outpatient
Opioid use disorder on medication assistance treatment
Prolonged QTc >500ms
Chronic kidney disease with eGFR < 30mL/min