Oral Methadone in Cardiac Surgery

Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorMayo Clinic

About this trial

The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anesthesia on postoperative pain for patients undergoing elective cardiac surgery.

Eligibility criteria

Qualifiers

None

Disqualifiers

Chronic pain requiring opioid medications as an outpatient

Opioid use disorder on medication assistance treatment

Prolonged QTc >500ms

Chronic kidney disease with eGFR < 30mL/min

Trial design

Treatments tested in this trial

  • Methadone, oral
  • Methadone, intravenously

Treatment groups

100 Participants
are divided into 2 treatment groups

Sponsors and collaborators