About this trial
To evaluate the effects of preoperative prophylactic administration of clindamycin vaginal cream compared to preoperative vaginal cleansing using a 10% povidone-iodine solution on postpartum infectious morbidity.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
female participants with singleton pregnancies scheduled for elective cesarean sections at term, specifically between 37 and 40 weeks of gestation
free from any medical disorders.
The participants' ages ranged from 18 to 40 years
body mass index (BMI) ranged from 18 to 30 kg/m2
Disqualifiers
Cases of urgent or emergent CS.
Abnormal vaginal secretion (bad smelling yellowish secretion, whitish cheesy discharge with pruritus, bloody discharge; etc…).
Women with medical disorders such as pre-gestational diabetes, anemia, hypertension, preeclampsia, or immunosuppressant pregnant women.
Women who had a skin infection adjacent to the operative site.
Trial design
Parallel
Treatments tested in this trial
Clindamycin vaginal cream
DrugClindamycin vaginal cream one applicator each night for 3 nights before CS.
Vaginal preparation with povidone- iodide solution 10 %
DrugVaginal preparation with povidone- iodide solution 10 %
Treatment groups
Trial outcomes
Primary outcomes
Wound infection (surgical site infection SSI)
erythema, tenderness or wound edge separation with purulent discharge involving the cesarean incision site.
Sponsors and contacts
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