Health TrialsbyHealthPanel

Preoperative Dexamethasone Injection to Improve Local Anesthesia Success in Endodontic Treatment

ConditionSymptomatic Irreversible Pulpitis
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18-60
SponsorWatim Medical & Dental College

About this trial

This study aims to determine whether giving a single dose of 4mg dexamethasone before root canal treatment can reduce the amount of pain patients experience during the procedure . Patients diagnosed with symptomatic Irreversible Pulpitis requiring endodontic treatment will be enrolled. Participants will receive either dexamethasone or placebo before treatment , and pain during the procedure will be measured using a Visual Analogue Scale (VAS) .

The findings may help improve pain management strategies during root canal treatment .

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients with pain VAS >/= 6

Carious exposed mandibular molar with symptomatic irreversible pulpitis

Patients between ages 18-60 years

American Society of Anesthesiologists class I or II medical histories -

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • dexamethasone

    Drug

    participants receive 4mg dexamethasone administered via intraligamental infiltration followed by inferior alveolar nerve block before endodontic treatment of mandibular molars with symptomatic irreversible pulpitis

  • Saline (0.9% NaCl)

    Drug

    participants receive an equivalent volume of normal saline administered via intraligamental infiltration before root canal treatment for symptomatic irreversible pulpitis

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: Dexamethasone GroupExperimental treatment 1 intervention
Group B: SalinePlacebo comparator 1 intervention

Trial outcomes

Primary outcomes

1

Intraoperative pain intensity

intraoperative pain intensity measured using the Heft-parker Visual Analogue Scale following root canal treatment

Time frame
Pain intensity assessed intraoperatively from initiation of access cavity preparation until completion of canal instrumentation during a single visit ( approximately 30-90 minutes).

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Watim Medical & Dental College

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: