This study will see if a blue dye (methylene blue) given into a vein, together with a special camera light, helps surgeons find the left ureter (the tube from the kidney to the bladder) faster during left-sided bowel surgery. Adults having open, laparoscopic, or robotic left-sided colorectal surgery will be randomly assigned to either the blue dye with special light or standard white light alone. The main question is whether the blue dye method finds the ureter more quickly, which could make the operation safer.
Aged ≥18 years
Scheduled to undergo open, laparoscopic or robotic left-sided colorectal surgery, including left colectomy, high anterior resection, low anterior resection, abdominoperineal resection, subtotal colectomy and total colectomy.
Unable to understand the aims and objectives of this study and unable to give consent for participation
Known allergy to methylene blue
Pregnant
Taking selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, monoamine oxidase inhibitors, or tricyclic antidepressants (risk of serotonin syndrome)
Parallel
Intravenous Methylene blue
DrugIntravenous methylene blue 0.5-1.0 mg/kg administered intraoperatively for fluorescence ureter identification.
Fluorescence Imaging Device for Methylene Blue
DeviceModified Stryker 1688 Fluorescence Laparoscopic System with additional filter
Time to identification of the left ureter
Time (in minutes) from peritoneal incision to first visualisation of the left ureter during left-sided colorectal surgery.
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This trial is not recruiting at the moment. You can still explore other options:
