Spinal Anesthesia With Bupivacaine Versus Prilocaine on Postoperative Shivering After Inguinal Hernia Repair

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age20-60
SponsorAmr mohamed

About this trial

Effect of spinal anesthesia with bupivacaine versus prilocaine on postoperative shivering after inguinal hernia repair : a prospective randomized double blind study

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

patients with inguinal hernia under spinal anesthesia aged from 20 to 60 years

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • Bupivacaine Spinal Anesthesia

    Drug

    Group B: (n=40) patients receiving hyperbaric bupivacaine 0.5% (Marcaine, Sunny Medical, Egypt).

  • Prilocaine spinal anesthesia

    Drug

    Group P; (n=40) will receive prilocaine2% (Takipril, Sunny Medical, Egypt).

  • Spinal Anesthesia (bupivacaine) spinal anesthsia (prilocaine)

    Drug

    In both groups the patients will be in the sitting position after preparation and draping of the patient's back. A skin wheal will be made by 1 ml of lidocaine HCl 2% at L3-4 interspace using a 25-gauge needle. Hyperbaric bupivacaine 0.5% will be given in dose (15mg) in group B and hyperbaric prilocaine2% in dose (60mg) in Group P. Anesthesia will be prepared by personnel not involved in this study. Patients will be supplemented with oxygen 5.0 l/minute by face mask. Time to achieve T10 dermatome will be recorded also motor level by modified Bromage motor blockade score; 4=no motor block, 3=can flex leg at knee, 2=can flex leg at the ankle and 1= complete motor block. The time needed to reach the maximum block will be recorded. In both groups the hemodynamic parameters will be recorded before block, immediately after block then every 5 min till end of the operation. Need for sedation or analgesia will be recorded.

Treatment groups

80 Participants
are divided into 2 treatment groups
Group A: Prilocaine groupActive comparator 2 interventions
Group B: Buivacaine groupActive comparator 2 interventions

Trial outcomes

Primary outcomes

1

shivering using bedside shivering assesement score ( BSAS)

Time frame
one year
2

shivering using bedside shivering assesement score ( BSAS)

shivering using bedside shivering assesement score ( BSAS)

Time frame
1 year

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Amr mohamed

Lead sponsor

Theodor Bilharz Research Institute

Sponsor institution

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