About this trial
This randomized, double-blinded volunteer study compares two ways of performing the adductor canal (AC) nerve block at the mid-thigh to see which approach more reliably numbs the anteromedial knee. One approach is the traditional AC block placed near the saphenous nerve; the other separately targets the nerve to vastus medialis (NVM) in addition to the saphenous nerve. Healthy adult participants receive both blocks in one visit (one on each leg), with the order randomized. The primary outcome is change in quadriceps strength (a proxy for vastus medialis anesthesia) measured by load-cell dynamometry. Secondary outcomes include cutaneous sensory mapping (pinprick and cold) and the percentage of a standardized, marked knee-incision line covered by sensory block. The study uses ultrasound guidance and a standard dose of chloroprocaine, with routine monitoring to minimize risks.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Age ≥18 years
Able to provide written informed consent
Able and willing to comply with study procedures and ~6-hour visit
American Society of Anesthesiologists (ASA) Physical Status 1 or 2
Disqualifiers
BMI >35 kg/m²
Use of analgesics within 24 hours before the procedure
History of thigh trauma or surgery
Pregnant or planning pregnancy
Trial design
Crossover
Treatments tested in this trial
Traditional adductor canal block
Procedure/SurgeryUltrasound-guided injection adjacent to the saphenous nerve; 20 mL of 2% chloroprocaine.
NVM (nerve to vastus medialis) targeted adductor canal block
Procedure/SurgeryUltrasound-guided injection; 10 mL 2% chloroprocaine at the NVM (confirmed by nerve stimulation), plus 10 mL at the saphenous nerve.
Chloroprocaine Injection
Drug2% chloroprocaine
Treatment groups
Trial outcomes
Primary outcomes
Quadriceps strength as measured by load cell dynamometer
Load cell dynamometers are highly accurate portable electronic devices used to measure isometric muscle strength.
Secondary outcomes
Percentage of hypothetical incision covered
An unblinded anesthesiologist will mark the mock total knee arthroplasty and the length of the hypothetical incision that has diminished sensation to pinprick will be determined.
Locations
Sponsors and contacts
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This trial is not recruiting at the moment. You can still explore other options: