TES RCT Fleet Enema vs Oral Mechanical Bowel Prep

Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18-75
SponsorNova Scotia Health Authority

About this trial

There is no consensus about the best bowel preparation prior to transanal endoscopic surgery TES). Cleanliness and visibility in the rectosigmoid and rectum are of utmost importance, possibly even more so than during colonoscopy, to facilitate safe, precise and efficient resection of the rectal lesion and potentially adequate closure of the defect. Both Fleet enemas and oral mechanical bowel preparation are considered standard of care in preparation for TES. This single center two arm single blinded randomized controlled trial will compare the effectiveness of Fleet enemas in comparison to Pico Salax oral mechanical bowel preparation in cleansing the rectum as measured by a modified version of the Ottawa Bowel Prep Scale.

Eligibility criteria

Qualifiers

undergoing transanal endoscopic surgery at the QEII Health Sciences Center in Halifax by one of the colorectal trained surgeons

Disqualifiers

chronic constipation not well controlled with diet or stool softening agents

previous pelvic radiation

inflammatory bowel disease

repeat transanal surgery for the same lesion

Trial design

Treatments tested in this trial

  • Fleet Enema
  • Pico-Salax

Treatment groups

66 Participants
are divided into 2 treatment groups

Sponsors and collaborators