Scoliosis correction surgery in children is a complex procedure with significant risks, including postoperative pain, inflammatory response, and potential neurological complications. Effective pain control and minimizing inflammation are critical for faster recovery and improved patient outcomes. Dexamethasone is commonly used as an adjuvant in regional anesthesia due to its anti-inflammatory effects and ability to prolong analgesia. However, limited research exists on the optimal route of dexamethasone administration (intravenous vs. perineural) and the best local anesthetic concentration for pain management, inflammatory response, and neuromonitoring during surgery.
This study aims to compare the effects of different dexamethasone administration routes and local anesthetic concentrations on postoperative pain, inflammation (NLR, PLR), and neuromonitoring in pediatric scoliosis surgery. Results may improve regional anesthesia protocols, enhance patient safety, and offer valuable insights for clinical practice.
>10 and <18 years old
scheduled for idiopathic scoliosis surgery
included infection at the site of the regional block,
coagulation disorders,
immunodeficiency,
American Society of Anesthesiologists (ASA) physical status of IV or higher,
Parallel
perineural Dexamethasone
DrugErector Spinae Plane Block with 0.2% Ropivacaine + 0.1mg/kg perineural Dexamethasone
intravenous Dexamethasone
DrugErector Spinae Plane Block with 0.2% Ropivacaine + 0.1mg/kg intravenous Dexamethasone
Time to first rescue opioid analgesia
Time to first rescue opioid analgesia
intraoperative requirement for propofol
intraoperative requirement for propofol in mg/kg
intraoperative requirement for remifentanil
intraoperative requirement for remifentanil in ug/kg
MEP
Motor evoced potentials durring surgery
Total opioid consumption
Total opioid consumption in milliequivalents of morphine per kg
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