Under the premise of basic treatment, to explore the improvement effect of huperzine A injection on short-term and long-term neurocognitive dysfunction in patients with aneurysmal subarachnoid hemorrhage after interventional/surgical treatment.
Age 18-70;
The patients were proved to be aneurysmal subarachnoid hemorrhage by imaging examination (head CT, CT angiography (CTA), whole brain angiography (DSA));
Hunt Hess was graded I-III at admission;
The patients were treated with endovascular therapy or craniotomy and clipping surgery;
Non aneurysmal subarachnoid hemorrhage;
Cognitive dysfunction existed before onset;
Patients with angina pectoris, bronchial asthma, mechanical intestinal obstruction, liver and kidney insufficiency, and urinary tract obstruction;
Complicated with other nervous system diseases, including nervous system degenerative diseases (Alzheimer's disease, Parkinson's disease, Lewy body dementia, frontotemporal dementia, etc.), neuromyelitis optica, epilepsy, central nervous system infection (such as AIDS, syphilis, etc.), brain traumatic dementia, etc;
Wanbangde Pharmaceutical Group Co., LTD
Lead sponsor
Second Affiliated Hospital, Zhejiang University, School of Medicine
Collaborator