The Efficacy of Doxycycline Post Exposure Prophylaxis for Preventing STIs Among MSM in Bangkok, Thailand.
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexMale
Age18-60
SponsorBangrak STIs Center
About this trial
The objective of this research is to evaluate the efficacy and safety of doxycycline in MSM for preventing sexually transmitted infections (gonorrhea, chlamydia, and syphilis) in Thailand
Participation in this study will last approximately 12 weeks and will include 2-3 clinic visits, along with 10-11 follow-up phone contacts over a period of 11 weeks.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
History of allergy to tetracycline-class antibiotics
Trial design
Design model
Parallel
Treatments tested in this trial
Doxycycline (200mg/day)
DrugDoxycycline 200 mg single dose after unprotected sex within 24-72 hours
Treatment groups
400 Participants
are divided into 2 treatment groupsGroup A: DoxyPEP armExperimental treatment 1 intervention
Group B: Control armNo intervention 0 interventions
Trial outcomes
Primary outcomes
1
To evaluate the efficacy of doxycycline in preventing sexually transmitted infections (gonorrhea, chlamydia, and syphilis) among men who have sex with men in Thailand.
Measure the proportion of participants who test positive by NAAT for gonorrhea or chlamydia at any anatomical site (genital, pharyngeal, or rectal), or who are diagnosed with syphilis during the study period.
Time frame
12 weeksSponsors and contacts
Click on the lead sponsor to view all of their trials.
Bangrak STIs Center
Lead sponsor
Mahidol University
Collaborator
Source ClinicalTrials.gov