Tranexamic Acid Versus Blood Stopper Treatments in Epistaxis Management

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorAnkara Ataturk Sanatorium Training and Research Hospital

About this trial

In this randonmized controlled trial, aim to compare the effectiveness of local administration of tranexamic acid and blood stopper (Ankaferd®) on cessation of bleeding in epistaxis patients.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients over 18 years of age with epistaxis will present to the emergency department with non-traumatic epistaxis and whose bleeding do not stop with simple external compression for 10 minutes.

Disqualifiers

Patients demonstrating hemodynamic instability

Patients with documented allergy to tranexamic acid or Ankaferd

patients with known bleeding disorders,

patients using anticoagulants,

Trial design

Design model

Parallel

Treatments tested in this trial

  • Blood Stopper (Ankaferd)

    Drug

    5 ml of Ankaferd® will be sprayed through the bleeding side nostril and external nasal pressure will be performed for 10 minutes.

Treatment groups

186 Participants
are divided into 2 treatment groups
Group A: Tranexamic acidActive comparator 1 intervention
Group B: Blood Stopper (Ankaferd)Experimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Cessation of bleeding

Primary outcome was definition cessation in bleeding at 10-minutes after performing local drug interventions.

Time frame
10-minutes after performing local drug interventions.

Secondary outcomes

1

Re-bleeding

The secondary outcome was a comparison of the re-bleeding rate within 24 hours in the two treatments groups.

Time frame
From cessation of bleeding to re-bleeding within 24-hours.

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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