GBM patients receiving PDT treatment (50 cases，surgery combined with photodynamic therapy) and traditional treatment (50 cases，traditional surgery) in our hospital and partner hospitals were collected. The prognosis was analyzed by comparing with the control group from multiple perspectives such as image evaluation, imaging effect, Karnofsky score, median survival time and survival rate.
None
Photosensitizer allergy.
Severe coagulation disorder.
Patients with severe cardiovascular and cerebrovascular diseases, especially patients in the acute stage.
Multiple organ failure, end-stage patients. ⑤ Pregnant women: Photofrin is considered a class C pregnancy risk (toxic, non-teratogenic) drug with non-dialysis properties.
GBM patients recevied traditional treatment options (including surgery combined with radiotherapy and chemotherapy) or PDT treatment
Case-control
Prospective
Photodynamic therapy (PDT)
Procedure/SurgeryGBM patients recevied surgical combination photodynamic therapy
GBM patients recevied traditional treatment options
Procedure/SurgeryGBM patients recevied traditional treatment options (including surgery combined with radiotherapy and chemotherapy)
Number of Participants with Treatment of Surgical combination Photodyanmic therapy
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Zhejiang Provincial People's Hospital
Lead sponsor
The Second Affiliated Hospital of Harbin Medical University
Collaborator
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