Photon-Counting CT Versus Conventional CT for Carotid Plaque Assessment in Patients With Carotid Artery Stenosis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age10-90
SponsorChinese PLA General Hospital
About this trial
This prospective observational study aims to compare photon-counting detector computed tomography angiography (PCD-CTA) with conventional energy-integrating detector computed tomography angiography (EID-CTA) for the assessment of carotid atherosclerotic plaques in patients with carotid artery stenosis.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age 18 years or older.
Patients with carotid atherosclerotic plaque or carotid artery stenosis.
Patients scheduled to undergo carotid artery stenting.
Patients undergoing preprocedural carotid CTA examination.
Disqualifiers
Known allergy to iodinated contrast material.
Severe renal insufficiency or other contraindications to contrast-enhanced CT.
Pregnancy or suspected pregnancy.
Severe motion or other artifacts resulting in nondiagnostic image quality.
Trial population
The study population will consist of patients with carotid atherosclerotic stenosis referred for carotid CT angiography. Eligible participants will be prospectively enrolled before carotid artery intervention.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
100 Participants
are grouped into 1 trial groupGroup A: Patients With Carotid Artery Stenosis
Trial outcomes
Primary outcomes
1
Carotid Plaque Visualization and Characterization on PCD-CTA Compared With Conventional EID-CTA
Carotid atherosclerotic plaques will be independently evaluated on photon-counting detector CTA and conventional energy-integrating detector CTA.
Time frame
1-4 yearsSecondary outcomes
1
Contrast-to-noise ratio on PCD-CTA compared with conventional EID-CTA
Contrast-to-noise ratio (CNR) will be quantitatively calculated from measurements obtained on PCD-CTA and conventional EID-CTA using a predefined measurement method. CNR values will be compared between the two CT techniques.
Time frame
1-4yearsSponsors and contacts
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Source ClinicalTrials.gov