Physiopathology of Behavioral Addictions and Biomarkers
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorNantes University Hospital
About this trial
The goal of this observational study is to evaluate the expression of miR-10a-5p in the blood in patients with sexual addiction or food addiction. The main question it aims to answer is : To determine whether adults patients with SA or FA exhibit a distinct blood miR-10a-5p expression profile compared with matched healthy controls.
For all participants, one blood sample will be collected.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Male and females ≥ 18 years old
Already in care or newly initiating care
Participating to EVALADD cohort
Current diagnosis of FA
Disqualifiers
Presence of a current diagnosis of SA
Presence of any current addictive disorder (substance [except tobacco] use disorders, gambling disorder, gaming disorder)
Presence of any current instable psychiatric disorder (requiring the initiation or adapation of medication)
Pregnancy or breastfeeding woman
Trial population
Patients with food or sexual addiction, compared with age- and sex-matched healthy controls with no current addictive disorder.
Trial design
Design model
Case-control
Time perspective
Prospective
Treatments tested in this trial
blood sampling
Biological/VaccineOne blood sample wiil be collected into a 10mL K2EDTA BD Vacutainer® tube
Treatment groups
28 Participants
are divided into 2 treatment groupsGroup A: Patients with addiction1 intervention
Group B: Healthy controls1 intervention
Trial outcomes
Primary outcomes
1
Blood miR-10a-5p expression
The concentration of each miR-enriched fraction will be determined by spectrophotometric between patients with SA or FA and matched healthy controls.
Time frame
3 monthsSecondary outcomes
1
Blood additional circulating miRs expression
The concentration of circulating miRs fraction will be determined by spectrophotometric between patients with SA or FA and matched healthy controls.
Time frame
3 months2
Clinical Characteristics
Association between blood expression levels of circulating miRs and age
Time frame
3 months3
Clinical Characteristics
Association between blood expression levels of circulating miRs and sex
Time frame
3 months4
Clinical Characteristics
Association between blood expression levels of circulating miRs and duration of addiction
Time frame
3 monthsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Nantes University Hospital
Lead sponsor
INSERM U1216 Grenoble Institut des Neurosciences
Collaborator
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: