The goal of this pilot clinical trial is to study is to test the feasibility and effects of a virtual (remote) version of a cognitive rehabilitation intervention - Memory, Attention, and Problem Solving Skills for Persons with MS (MAPSS-MS). We have already tested this intervention "in person" and found it to be effective at helping persons with MS improve their cognitive function learn. We are now testing the MAPSS-MS intervention using a virtual or remote format. The main questions this pilot study aims to answer are:
1. What is the feasibility of the Virtual MAPSS-MS intervention 2. Compared with persons in the wait list control group, will persons receiving the Virtual MAPSS-MS intervention have better overall neurocognitive function and 3. ) Compared with persons in the wait list control group, will persons receiving the Virtual MAPSS-MS intervention have improved stress, self-efficacy for cognitive everyday tasks, use of compensatory strategies and improved depressive symptoms, fatigue, sleep and pain.
Participants will be asked to take part in the MAPSS-MS intervention virtually and complete surveys and cognitive tests online at three time points: before the eight-week intervention, immediately after the intervention and six-weeks after the intervention.
The virtual MAPSS-MS has two components (a) Group sessions via zoom with an expert leader and (b) a computer assisted brain games (Brain HQ) program. The eight online group sessions (2 hours once per week) will address common cognitive concerns experienced by persons with MS and strategies that may be helpful. Participants will also be provided access to Brain HQ, a computerized training program, and asked to practice these games for 20-30 minutes on 5 or 6 days per week.
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Virtual Memory, Attention, and Problem Solving Skills for Persons with MS (MAPSS-MS)
BehavioralThis is a pilot test of the MAPSS-MS intervention in a virtual delivery format.
Neurocognitive Function -Objective
The Neurocognitive Index (NCI) score will be obtained via remote administration of the CNS Vital Sign's (CNS Vital Signs, LLC) Core computerized neurocognitive test battery. Batteries will be administered on participant's own computers. The core battery includes seven tests for verbal and visual memory, reaction time, processing speed, executive function, simple attention and motor speed, and five domain scores for composite memory, psychomotor speed, reaction time, cognitive flexibility, and complex attention The Neurocognitive Index is the average of five domain scores, representing a global score of neurocognition.
Perceived Cognitive Function PROMIS v2.0 - Cognitive Function-Abilities Short Form 8a
The PROMIS v2.0 - Cognitive Function-Abilities Short Form 8a includes 8 items that assess patient-perceived cognitive deficits including the areas of mental acuity, concentration, verbal and nonverbal memory, and verbal fluency.
Self-Efficacy for Cognitive Tasks
The Self-Efficacy for Cognitive Everyday Tasks - Part IV consists of 25 items; that assess beliefs regarding one's ability to recognize, monitor and manage cognitive everyday cognitive activities (e.g. paying bills, recalling a list, planning).
Depressive Symptoms - CES-D 10
The CES-D - Short Form includes 10 item that measure the frequency of depressive symptoms during last 7 days. There is a 4-point item response scale from rarely/none of the time to most/all of the time.Higher scores indicate more frequent depressive symptoms.
Compensatory Strategies
The Strategies to Improve Cognitive Function is a 20 item scale that assesses the use of compensatory strategies in everyday life. Higher scores indicate greater use of strategies.
Perceived Stress
The Perceived Stress Scale includes 10 items that measure inidivual's perception of stress during the last month related to everyday challenges and life. Higher scores indicate greater perceived stress.
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