Pitch Perception and Memory: Deficits and Training
ConditionCochlear Implants
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age5-90
SponsorHospices Civils de Lyon
About this trial
Pitch perception and memory are central in auditory cognition, in particular for sound source segregation and recognition, speech prosody and music processing. Here the investigator assess pitch perception and memory in hearing-impaired listeners wearing cochlear implant(s) and listeners with congenital amusia, both compared with control listeners. Behavioral, EEG, and MEG measures are collected in audio and audio-visual contexts to characterize pitch processing deficits, and test a pitch training program.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Aged between 18 and 90
Absence of neurological and psychiatric disorders
No major cognitive deficit, ability to understand and apply study instructions
Motivation to participate efficiently in the study
Disqualifiers
Age below 18 or above 90
Pregnant or breast-feeding woman
Trial design
Design model
Crossover
Treatments tested in this trial
Listening tests. Pitch training protocol
BehavioralThe two training protocols consists of perceptual tasks (auditory or visual exercises) performed repetitively using a tablet. Each protocol consists in 30 sessions of \~20 minutes performed at home over a period of 15 weeks.
visuo-spatial training protocol
BehavioralThe two training protocols consists of perceptual tasks (auditory or visual exercises) performed repetitively using a tablet. Each protocol consists in 30 sessions of \~20 minutes performed at home over a period of 15 weeks.
EEG/MEG/MRI recordings.
BehavioralListening tests. EEG/MEG/MRI recordings
Treatment groups
960 Participants
are divided into 3 treatment groupsGroup A: Cochlear implant usersExperimental treatment 3 interventions
Group B: Participants with Congenital AmusiaExperimental treatment 3 interventions
Group C: Control ParticipantsExperimental treatment 3 interventions
Trial outcomes
Primary outcomes
1
percentages of correct responses in listening tests
Time frame
during procedure2
reaction times in listening tests
Time frame
during procedure3
Event-Related Fields
MEG measurements
Time frame
during procedure4
Oscillations
MEG measurements
Time frame
during procedureSecondary outcomes
1
percentages of correct responses
Performance in listening tests in audio contexts
Time frame
Day 02
percentages of correct responses
Performance in listening tests in audio-visual contexts
Time frame
Day 03
reaction times
Performance in listening tests in audio contexts
Time frame
Day 04
reaction times
Performance in listening tests in audio-visual contexts
Time frame
Day 0Sponsors and contacts
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Source ClinicalTrials.gov