Plaque Burden and Ischemia in MINOCA
ConditionMINOCA
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Bergen
About this trial
The goal of this clinical trial is to assess coronary artery plaque burden, perivascular inflammation and extent of myocardial ischemia in patients presenting with acute myocardial infarction and non-obstructive coronary artery disease. The main question it aims to answer are:
* Identify coronary artery anatomy, plaque burden, composition and high-risk plaque features by CT coronary angiography in MINOCA * Assess presence, extent and severity of myocardial ischemia in MINOCA
Participants will examined by CT coronary angiography and stress \[12N\] NH3 PET-MR.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Acute chest pain
Elevated troponin
Non-obstructive coronary arteries by coronary angiography
Disqualifiers
Obstructive coronary artery disease
Contraindications against CT coronary angiography or stress [12N] NH3 PET-MR
Not able to give informed consent
Trial population
Patients hospitalized with acute myocardial infarction and non-obstructive coronary artery disease by coronary angiography
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
CT coronary angiography and [12N] NH3 PET-MR
Diagnostic testAdvanced coronary artery plaque analysis, myocardial ischemia and coronary flow reserve
Treatment groups
100 Participants
are divided into 1 treatment groupGroup A: CT coronary angiography and [12N] NH3 PET-MR1 intervention
Trial outcomes
Primary outcomes
1
Plaque burden
Time frame
1 week2
Myocardial ischemia
Time frame
1 weekSponsors and contacts
Click on the lead sponsor to view all of their trials.
University of Bergen
Lead sponsor
Haukeland University Hospital
Collaborator
Haraldsplass Deaconess Hospital
Collaborator
Source ClinicalTrials.gov