Platelet Rich Plasma Testis Treatment for Infertile Men
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age18+
SponsorStanford University
About this trial
Investigate the effect of intratesticular injection of autologous platelet rich plasma (PRP) on sperm retrieval rates and IVF outcomes in infertile men who already underwent a negative sperm retrieval. Currently, there is no alternative treatment after failed TESE. Prior series suggest that intratesticular PRP injections may improve TESE outcomes. We hope to determine whether PRP is an effective treatment for this patient population.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Men over the age of 18 diagnosed with NOA and at least one failed TESE, negative mapping or negative biopsy
Disqualifiers
None
Trial design
Design model
Single group
Treatments tested in this trial
Platelet rich plasma
Biological/VaccinePatients will undergo a blood draw (12 tsp) to prepare the PRP infusion. The use of a centrifuge and an Arteriocyte Magellan kit are necessary for the PRP preparation. After injection of local anesthesia, PRP will be injected into each testicle. * On the third month after the testicular PRP procedure, a TESE will be performed * If the procedure is successful a new IVF cycle using the sperm procured from the procedure will be done.
Treatment groups
10 Participants
are divided into 1 treatment groupGroup A: Platelet rich plasma treatment armExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
sperm present
A TESE procedure will be performed to determine if sperm are present
Time frame
3 months after PRP injectionSponsors and contacts
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Source ClinicalTrials.gov