POCUS Screening for TAA in Hypertensive Patients in the ED
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorChinese University of Hong Kong
About this trial
The investigators are going to recruit hypertensive patients in the emergency department of Prince of Wales Hospital. Point-of-care ultrasound of the aorta and measurements of the aortic diameter will be obtained. Other relevant clinical data will also be obtained for analysis. The primary outcome is the number of patients with a maximum aortic diameter of ≥ 4.5 cm and/or ≥ 50% localized enlarged diameter relative to the adjacent normal segment as indicated by POCUS.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Adult patients aged ≥ 18 years attending the ED during the study period
Known history of hypertension or newly diagnosed hypertension in the ED
Disqualifiers
Known history of aortic aneurysm or dissection
Previous thoracic aortic interventions or endovascular stenting
Patients in cardiopulmonary resuscitation
Traumatic patients
Trial population
hypertensives patients attending the emergency department without known history of aortic diseases.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Point-of-care ultrasound
Diagnostic testPOCUS screening will be conducted to measure the maximum diameters at end diastole of the aortic root, ascending aorta, aortic arch, and descending thoracic aorta.
Treatment groups
1,483 Participants
are divided into 1 treatment groupGroup A: hypertensive patients presenting to the emergency department1 intervention
Trial outcomes
Primary outcomes
1
number of patients with a dilated aorta
is the number of patients with a maximum aortic diameter of ≥ 4.5 cm and/or ≥ 50% localized enlarged diameter relative to the adjacent normal segment as indicated by POCUS
Time frame
Day 1Secondary outcomes
1
number of patients with confirmed TAA
number of patients with confirmed TAA as verified by CTA
Time frame
through study completion, an average of 1 yearOther outcomes
1
BMI for all participants
BMI in kg/m\^2
Time frame
at the time of recruitment2
number of CTA scans
number of CTA scans conducted for TAA confirmation
Time frame
through study completion, an average of 1 year3
number of surgical interventions
number of surgical interventions performed among TAA patients
Time frame
from recruitment to 28 days after4
ICU and hospital length of stay
ICU and hospital length of stay among patients with treatment for TAA
Time frame
through study completion, an average of 1 yearSponsors and contacts
Click on the lead sponsor to view all of their trials.
Chinese University of Hong Kong
Lead sponsor
Hospital Authority, Hong Kong
Collaborator
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: