About this trial
This will be a prospective, observational, case-control study of adult patients presenting to the WellSpan York Hospital Emergency Department (YHED) with signs and symptoms of esophageal food or foreign body impaction. Point of care ultrasound (POCUS) will then be performed by a trained emergency physician to collect ultrasound data, including the presence or absence of direct visualization food bolus/foreign body, as well as secondary markers of dilatation, such as maximal esophageal area. Investigators will also enroll an age/sex-matched control group of asymptomatic individuals to establish baseline esophageal measurements.
Patients will otherwise receive medical treatment per standard of care. Subsequent interventions will also be documented, including glucagon, carbonated beverages, and esophagogastroduodenoscopy (EGD). If patients remain in the ED and improve without need for EGD they will undergo repeat ultrasound. Chart review at 1 month will be performed to establish results of EGD including improvement, recurrence, or presence of pathologic abnormalities. The investigators aim to establish normal and abnormal parameters to aid in the diagnosis of esophageal food impactions to predict need for definitive EGD management.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Age ≥18 years
Signs and symptoms of esophageal food bolus or foreign body
Disqualifiers
Prior esophageal surgery
History of head/neck cancer
Incarcerated individuals
Individuals unable to provide consent
Trial population
This will be a case-control study of adult patients presenting to the WellSpan York Hospital Emergency Department (YHED) with signs and symptoms of esophageal food or foreign body impaction. We will also enroll an age/sex-matched control group of asymptomatic individuals to establish baseline esophageal measurements.
Trial design
Case-control
Prospective
Treatments tested in this trial
Point of care ultrasound
Diagnostic testPoint of care medical ultrasound machines will be used to sonographically visualize the esophagus and following sonographic data will be collected: * Presence/absence of suspected foreign body * Sonographic esophageal measurements (diameters, area) * Other relevant secondary sonographic findings
Treatment groups
Trial outcomes
Primary outcomes
Presence or absence of esophageal foreign body/food impaction
Presence of absence of esophageal foreign body/food impaction on esophagogastroduodenoscopy
Secondary outcomes
Number/proportion of subjects experiencing resolution of symptoms with standard medical therapies
Number/proportion of subjects experiencing resolution of symptoms with standard medical therapies, including glucagon and carbonated beverages
Number/proportion of subjects requiring endoscopic intervention
Number/proportion of subjects needing interventional procedures during esophagogastroduodenoscopy due to esophageal symptoms
Sponsors and contacts
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