Post-Extraction Healing: microRepair vs Chlorhexidine
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorUniversity of Roma La Sapienza
About this trial
This randomized clinical trial evaluates the efficacy of a microRepair ABX mouthwash mousse compared to 0.20% chlorhexidine in promoting wound healing following tooth extraction. The study monitors clinical parameters such as pain, swelling, and healing indices at 1, 7, and 15 days post-surgery. The primary objective is to determine if the microRepair ABX technology enhances tissue regeneration and reduces post-operative complications.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Destructive caries that do not allow for conservative or prosthetic recovery.
Untreatable endodontic and/or periapical lesions.
Advanced periodontal lesions with significant loss of supporting tissue.
Traumatic lesions involving root fractures (vertical or at the middle third).
Disqualifiers
None
Trial design
Design model
Parallel
Treatments tested in this trial
microRepair ABX Mousse
Other interventionTopical application of the mousse on the surgical wound starting from the day after the extraction. The mousse is specifically formulated to promote healing through microparticles that accelerate tissue repair and an antibacterial complex to prevent localized infections.
CHX mouthwash 0.20%
Other interventionApplication of 0.20% Chlorhexidine liquid mouthwash. Used as a control treatment to evaluate the comparative effectiveness of the test product in reducing plaque, pain, and inflammation while promoting socket healing.
Treatment groups
30 Participants
are divided into 2 treatment groupsGroup A: Group Test: microRepair ABX MousseExperimental treatment 1 intervention
Group B: Group Control: CHX 0.20%Active comparator 1 intervention
Trial outcomes
Primary outcomes
1
Plaque Index at the Tooth Extraction Site
Assessment of the presence or absence of visible bacterial plaque at the tooth extraction site, recorded as a dichotomous variable (Yes/No). The absence of plaque indicates better oral hygiene and a lower risk of postoperative infection.
Time frame
From enrollment to the end of treatment at 15 days2
Gingival Condition of the Peri-Alveolar Tissue
Evaluation of the gingival tissue surrounding the extraction socket based on the presence or absence of clinical signs of inflammation (e.g., redness, edema), recorded as a dichotomous variable (Yes/No). The absence of inflammation indicates healthier gingival tissue.
Time frame
From enrollment to the end of treatment at 15 daysSecondary outcomes
1
Patient Satisfaction with the Product
Assessment of patient-reported satisfaction with the product using a structured questionnaire administered at the end of the treatment period. The questionnaire will evaluate overall acceptability of the product, including: * taste * comfort during application * perceived effectiveness * preference compared to traditional treatment * perceived improvement in sensitivity Each item will be recorded as a dichotomous variable (Yes/No) (e.g., satisfied vs. not satisfied). Higher frequency of positive responses indicates greater patient satisfaction.
Time frame
At 15 days post-treatmentSponsors and contacts
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Source ClinicalTrials.gov