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Post Oesophagectomy Outcomes in a Single Regional Centre in Australia

ConditionOesophageal Cancer
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorLaunceston General Hospital

About this trial

Literature review/rationale for project

* Oesophageal cancer is associated with a grim prognosis despite many advances in treatment. Oesophagectomy is a key component of the care of patients who are candidates for curative treatment, however it is associated with substantial morbidity. * Several studies have suggested that oesophagectomies performed at higher volume tertiary centres are associated with lower morbidity and mortality than lower volume centres, and this has prompted changes to policy in countries such as Great Britain, Canada and the Netherlands with regards to the centralisation of these cases. A higher volume centre within Australia is likely to perform 6 or more procedures per year. * Currently within Australia, centralisation on a large scale has not occurred. This has been limited in part by resource provision and geographical barriers. Therefore, oesophagectomies in Australia are still routinely performed in regional centres. However, there is a paucity of recent outcomes data from these centres.

Aims/objectives

* Retrospective review of oesophagectomies undertaken in a single regional centre in Tasmania, Australia over 10 years (January 2014 to December 2023) * Assess outcomes (long and short-term complications and mortality) and compare to morbidity and mortality rates from larger international centres

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

patients who underwent oeophagectomy at Launceston General Hospital between January 2014 to December 2023

Disqualifiers

none

Trial population

patients who underwent oeophagectomy at Launceston General Hospital between January 2014 to December 2023

Trial design

Design model

Case-only

Time perspective

Retrospective

Treatments tested in this trial

  • No Intervention: Observational Cohort

    Other intervention

    No intervention - retrospective observational study

Treatment groups

100 Participants
are divided into 1 treatment group
Group A: oesophagectomy1 intervention

Trial outcomes

Primary outcomes

1

mortality

date of death from any cause or date of palliation whichever came first

Time frame
from date of surgery to end of study (November 2024) for a timeframe up to 10 years
2

Anastomotic leak

Grade 1-3, diagnosed radiologicaly, requiring intervention (surgical or non-surgical)

Time frame
from date of surgery to end of study period (Nov 2024), assessed up to 10 years
3

Length of stay

total inpatient hospital stay and total ICU length stay

Time frame
from date of surgery to discharge date of hospital admission, approximately 2-4 weeks in most cases but assessed up to 12 weeks

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Launceston General Hospital

Lead sponsor

Department of Health, Tasmania

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: