Post-operative Cognitive Decline After Ambulatory Cataract Surgery in the Elderly Population

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65+
SponsorSamuel Lunenfeld Research Institute, Mount Sinai Hospital

About this trial

Postoperative cognitive decline is a recognized complication following anesthesia and surgery in older adults; however, its incidence after ambulatory cataract surgery performed under sedation is not well understood. This prospective observational study aims to determine the proportion of patients aged 65 years and older who develop postoperative cognitive decline at 3 weeks and 3 months following ambulatory cataract surgery.

Participants will complete a baseline Tele-Montreal Cognitive Assessment (T-MoCA) before surgery and repeat the assessment remotely at 3 weeks and 3 months after surgery. Demographic, medical, anesthetic, and procedural data will also be collected. The findings will improve understanding of postoperative cognitive outcomes in elderly patients undergoing ambulatory cataract surgery and help identify patients who may be at increased risk for postoperative cognitive decline.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

Inability to understand instructions in English

Lack of access to a computer, tablet, smartphone, or internet access

Patients with established cognitive deficit diagnoses (e.g. Alzheimer's, traumatic brain injury (TBI), stroke)

Patients with known psychiatric diagnoses

Trial population

Patients undergoing ambulatory cataract surgery at the Kensington Eye Institute (KEI).

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

300 Participants
are grouped into 1 trial group
Group A: Older Adults Undergoing Ambulatory Cataract Surgery

Trial outcomes

Primary outcomes

1

Proportion of patients with postoperative cognitive decline following sedation for ambulatory cataract surgery

The proportion of participants who demonstrate postoperative cognitive decline, defined as a decline of one standard deviation or greater from their baseline Tele-Montreal Cognitive Assessment (T-MoCA) score, assessed at 3 weeks and 3 months following ambulatory cataract surgery performed under sedation.

Time frame
3 months post-operatively

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital

Lead sponsor

Mount Sinai Hospital, Canada

Collaborator

Kensington Eye Institute

Collaborator

This trial is not recruiting at the moment. You can still explore other options: