About this trial
The investigator proposes to examine the effects of excitatory transcranial magnetic stimulation (TMS) combined with semantic feature analysis (SFA) language therapy to improve word-finding abilities in stroke survivors with aphasia (SWA).
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Diagnosed with left hemisphere stroke
Consent date >= 1 month after stroke onset
Fluent in English
18 years of age or older
Disqualifiers
Severe cognitive, auditory or visual impairments that would preclude cognitive and language testing
Presence of major untreated or unstable psychiatric disease (e.g. schizophrenia, bipolar disease)
A chronic medical condition that is not treated or is unstable
The presence of cardiac stimulators or pacemakers or intracardiac lines, neurostimulators, medication infusion device, any other implants near the scalp (e.g., cochlear implants) or in the eye, metal in the body (e.g., splinters, fragments, clips)
Trial design
Parallel
Treatments tested in this trial
Precision TMS with SFA
DeviceExcitatory TMS delivered using a precision site finding approach and intermittent theta burst stimulation protocol
Control TMS with SFA
DeviceExcitatory TMS using intermittent theta burst stimulation delivered to a control vertex site.
Treatment groups
Trial outcomes
Primary outcomes
Accuracy on a picture naming test
Changes in accuracy on untrained stimuli after SFA+TMS compared between groups (precision, control).
Sponsors and contacts
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