Post-Surgery Extracorporeal Life Support

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorUniversity of Florence

About this trial

Extracorporeal Life Support (ECLS) may provide pulmonary and circulatory support for patients with acute heart failure refractory to conventional medical therapy. However, indications and effectiveness of ECLS engagement post-surgery remains a concern. The investigators sought to analyze indications, modality and outcomes of PS-ECLS, to identify predictors of early and midterm survival after PS-ECLS. The investigators have recorded prospectively, and analysed data of 209 consecutive PS-ECLS patients between January 2004 and December 2018. Demographic and clinical data before, during and after PS-ECLS were collected and their influence on hospital mortality and outcomes (early and midterm) will analyse. Multivariate analysis of pre PS-ECLS implantation factors (as age, female sex , insulin-dependent diabetes, pulmonary hypertension, STS, type of surgical procedure data, pre-ECLS blood lactate level) will be made for identify prognostic risk factors of in-hospital mortality. Overall survival will be analysed, at 6 months,1-year and 5-years, respectively and the factors influencing mild/term outcome will be investigated.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients underwent cardiac surgery

Disqualifiers

Age < 18 years

Trial population

Patients underwent cardiac surgery

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • ECLS

    Procedure/Surgery

    Emergency application of Extracorporeal Life Support in post-surgical patients

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

Survival

Evaluate Early, mid and late Survival

Time frame
1 month after surgery
2

Survival

mid-time survival

Time frame
At 1 Year after surgery
3

Survival

late survival

Time frame
At 5 years after surgery

Secondary outcomes

1

Prognostic factors

Identify early and late negative and positive prognostic factors

Time frame
Early: 1 month after surgery
2

Prognostic Factors

Identify early and late negative and positive prognostic factors

Time frame
Late: 5 years after surgery

Other outcomes

Sponsors and contacts

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University of Florence

Lead sponsor

Sandro Gelsomino

Collaborator

Edvin Prifti

Collaborator

Francesco Cabrucci

Collaborator

Marco Bugetti

Collaborator

Orlando Parise

Collaborator

Aleksander Dokollari

Collaborator