About this trial
This study is designed to find out how different root canal sealers affect pain after root canal treatment. We are comparing two types of dental sealers: bioceramic sealer and calcium hydroxide sealer.
Participants who need root canal treatment will receive one of these sealers as part of their standard dental care. After the procedure, they will be asked to report any pain they experience for a few days.
The information from this study will help dentists choose sealers that may reduce post-treatment pain and improve patient comfort after root canal therapy.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients aged 18-40 years
Single-rooted permanent teeth
Teeth diagnosed with symptomatic irreversible pulpitis
Normal periapical condition on radiographic examination or periodontal ligament (PDL) space widening
Disqualifiers
Patients with systemic conditions that could alter the course of treatment
Teeth with immature root development
Teeth with necrotic pulp
Teeth exhibiting root resorption
Trial design
Parallel
Treatments tested in this trial
CeraSeal Bioceramic Sealer
Procedure/SurgeryParticipants will receive root canal obturation using CeraSeal Bioceramic Sealer. The sealer will be applied with a matching-taper gutta-percha cone using the single-cone technique after standard canal preparation and irrigation. The cavity will be sealed with glass ionomer cement. Postoperative pain will be recorded by participants using a Visual Analog Scale (VAS) at 12, 24, 48, and 72 hours.
Sealapex Calcium Hydroxide Sealer
Procedure/SurgeryParticipants will receive root canal obturation using Sealapex Calcium Hydroxide Sealer applied with a matching-taper gutta-percha cone using the single-cone technique after standard canal preparation and irrigation. Cavities will be sealed with glass ionomer cement. Postoperative pain will be recorded by participants using the VAS at 12, 24, 48, and 72 hours.
Treatment groups
Trial outcomes
Primary outcomes
Postoperative Pain Following Root Canal Obturation
Postoperative pain will be measured at 12, 24, 48, and 72 hours following root canal obturation. Pain intensity will be assessed using a Visual Analog Scale (VAS), where 0 represents "no pain," 1-3 indicates mild pain, 4-6 moderate pain, and 7-10 severe pain. Patients will record their pain scores at each time point, and any use of analgesics will also be documented to ensure accurate assessment.
Sponsors and contacts
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