Postoperative SpO₂/FiO₂ Ratio and Analgesic Methods in Laparoscopic Surgery

ConditionPostoperative Hypoxemia

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorIstinye University

About this trial

This prospective observational study aims to evaluate the association between postoperative oxygenation, assessed by the SpO₂/FiO₂ ratio, and body mass index (BMI), STOP-BANG score, and postoperative analgesic methods in patients undergoing elective laparoscopic cholecystectomy in the reverse Trendelenburg position. Postoperative SpO₂ and FiO₂ values will be recorded within the first postoperative hour, and the SpO₂/FiO₂ ratio will be calculated. Analgesic techniques applied as part of routine clinical practice will be documented. The study does not involve any additional intervention beyond standard care. The findings are expected to contribute to a better understanding of factors associated with early postoperative oxygenation and hypoxemia risk.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age ≥ 18 years

Patients who provide written informed consent

ASA physical status I-III

Patients undergoing elective laparoscopic cholecystectomy

Disqualifiers

Age < 18 years

Refusal or inability to provide informed consent

ASA physical status IV or higher

Known chronic respiratory diseases (e.g., asthma, COPD)

Trial population

The study population consists of adult patients aged 18 years and older with ASA physical status I-III who undergo elective laparoscopic cholecystectomy in the reverse Trendelenburg position. All participants provide written informed consent. Patients with significant respiratory or cardiovascular comorbidities, emergency surgery, or perioperative respiratory complications are excluded.

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

Standard of Care
Other intervention
No intervention is applied in this study. Patients are managed according to routine clinical practice. Demographic data, body mass index, STOP-BANG score, postoperative analgesic methods, and postoperative SpO₂ and FiO₂ values are recorded, and the SpO₂/FiO₂ ratio is calculated. All data are collected observationally without any additional procedures or changes to standard care.

Treatment groups

100 Participants

are divided into 2 treatment groups

Group A: Postoperative Observational Cohort1 intervention

Group B: control1 intervention

Trial outcomes

Primary outcomes

postoperative SpO₂/FiO₂ Ratio

The SpO₂/FiO₂ ratio calculated using peripheral oxygen saturation (SpO₂) and fraction of inspired oxygen (FiO₂) measured during the early postoperative period to assess postoperative oxygenation.

Time frame

Within the first postoperative hour (0-60 minutes after surgery)

Sponsors and contacts

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Istinye University

Lead sponsor

Source ClinicalTrials.gov

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