Postural Mobilization Compared to Noradrenaline Only in Off-Pump CABG Surgery

ConditionsCoronary Artery Disease With Need for Bypass Surgery Coronary Artery Disease(CAD)Coronary Artery Bypass Off Pump Coronary Artery Bypass Graft Off Pump Coronary Artery Bypass Surgery Hemodynamic Management Hemodynamic Optimization Noradrenaline

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorInfirmerie Protestante de Lyon

About this trial

This interventional prospective randomized study is designed to compare hemodynamic management using postural mobilization (+/- noradrenaline) versus noradrenaline only in patients undergoing open-heart coronary artery bypass graft (CABG) surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adult patient

patient requiring isolated coronary bypass surgery

Elective procedure or medical emergency

First cardiac surgery

Disqualifiers

Contraindication to an inotropic substance (only NA will be used)

Contraindication to passive leg raising

Patient in a life-threatening emergency

History of cardiac surgery

Trial design

Design model

Parallel

Treatments tested in this trial

passive leg raising for hemodynamic management during open-heart coronary bypass grafting
Procedure/Surgery
Passive leg raising will be used in the experimental group in order to manage hemodynamics: legs will be raised to an angle of approx. 45°
Use of Noradrenaline only in control group
Procedure/Surgery
Noradrenaline will be used for hemodynamic management. Passive leg raising will not be used in this group

Treatment groups

50 Participants

are divided into 2 treatment groups

Group A: Postural Group: hemodynamic management using postural mobilization (+/- noradrenaline)Experimental treatment 1 intervention

Group B: Control group: use of noradrenaline only (no postural mobilization)Active comparator 1 intervention

Trial outcomes

Primary outcomes

Assess use of noradrenaline in the experimental group (postural mobilization) vs control group (NA only) for hemodynamic management during open-heart coronary bypass graft surgery.

Time frame

From beginning to end of urgery

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Infirmerie Protestante de Lyon

Lead sponsor

Source ClinicalTrials.gov

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