PPI in Weaning Prediction
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorGaziosmanpasa Research and Education Hospital
About this trial
The aim of this study is to evaluate the predictive role of the Peripheral Perfusion Index (PPI) in forecasting extubation success during the weaning process in intensive care unit (ICU) patients. The study will investigate the ability of PPI to predict extubation failure by comparing it with traditional weaning criteria, including the Rapid Shallow Breathing Index (RSBI), PaO₂/FiO₂ ratio, and respiratory rate.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients who have been on mechanical ventilation for at least 48 hours
Patients over 18 years of age who are planned to undergo extubation following a spontaneous breathing trial (SBT)
Patients or their legal representatives who provide informed consent to participate in the study
Disqualifiers
Patients for whom extubation is not planned due to hemodynamic instability
Patients with peripheral vascular disease or a history of hand surgery
Patients who die or cannot be followed up during the study period
Trial population
Patients who have been on mechanical ventilation for at least 48 hours and Patients over 18 years of age who are planned to undergo extubation following a spontaneous breathing trial (SBT) Patients or their legal representatives who provide informed consent to participate in the study
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
patients were monitored for reentubation for 48 hours.
Other interventionpatients were monitored for reentubation for 48 hours.
weaning group
Other interventionpatients were monitored for reentubation for 48 hours.
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
• The ability of Peripheric Perfusion Index(PPI) measured 1 hour after extubation to predict extubation failure within 48 hours following extubation.
Time frame
48 hoursSecondary outcomes
1
• The predictive power of Peripheric Perfusion Index(PPI) measured at the beginning of the spontaneous breathing trial (SBT), at the 15th minute, at the end of SBT, and 2 hours after extubation in determining extubation success.
Time frame
3 hours2
• Correlation of Peripheric Perfusion Index(PPI) measurements between cardiac patients(Patients with at least one diagnosis of cardiac disease) and non-cardiac patients.
Time frame
48 hours3
Changes in Peripheric Perfusion Index(PPI) values in patients who experience spontaneous breathing trial(SBT) failure.
Time frame
48 hoursSponsors and contacts
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Source ClinicalTrials.gov