PRecision biomArker-Guided MAnagement of TuberculosIs Contacts: a Discrete Choice Experiment
ConditionTuberculosis (TB)
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity College, London
About this trial
This study is part of a broader programme of work to develop and pilot a randomised-controlled trial of new tests to identify people who will benefit most from preventive treatment for tuberculosis (TB). The aim of the current study is to explore factors affecting patient decisions to start preventive treatment. The specific objectives are to understand how patients make decisions about preventive treatment initiation for TB (stage 1); and to design and conduct a "discrete choice experiment" survey to further evaluate preferences (stage 2).
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Adults (aged ≥18 years) who have been tested for latent TB infection in routine clinical services, or are eligible for testing. Eligible people for testing include migrants from countries with high TB incidence (entered UK within 5 years), people with recent contact with a person with TB disease, and people eligible for LTBI screening prior to starting immunosuppression or through occupational health testing.
Disqualifiers
Unable to provide informed consent.
Trial population
1. Adults tested, or eligible for testing, for latent tuberculosis infection in routine clinical services. 2. Nurses, doctors or allied health professionals who have any experience of testing or treatment for TB or latent TB infection in UK services.
Trial design
Design model
Cohort
Time perspective
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
430 Participants
are grouped into 3 trial groupsGroup A: Patient participants for qualitative stage (stage 1)
Group B: Patient participants for discrete choice experiment (stage 2)
Group C: Healthcare worker participants for discrete choice experiment (stage 2)
Trial outcomes
Primary outcomes
1
Preventive treatment acceptance
Discrete choice experiment data will be analysed to evaluate the primary outcome of preventive TB treatment acceptance in the survey.
Time frame
BaselineSponsors and contacts
Click on the lead sponsor to view all of their trials.
University College, London
Lead sponsor
University of Aberdeen
Collaborator
Source ClinicalTrials.gov