Precision Medicine for Indolent Systemic Mastocytosis (PRISM)
ConditionSystemic Mastocytosis
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMayo Clinic
About this trial
This study is being done to better understand how symptoms of Systemic Mastocytosis (SM) relate to biological signals and to better understand how different treatments affect these signals.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Diagnosis of indolent systemic mastocytosis as defined by the World Health Organization 2022 criteria.
Doses of baseline treatment medications are stable for ≥ 14 days prior to enrollment.
Patient must have an Eastern Cooperative Oncology Group Performance Status of 0 to 2.
Disqualifiers
Diagnosis of advanced systemic mastocytosis defined by established criteria as outlined by the World Health Organization 2022 criteria.
Patient must not have had any cytoreductive therapy including but not limited to cladribine, interferon alpha, pegylated interferon, or antibody therapy < 28 days prior to enrollment.
Any other significant medical issue as determined by the principal investigator.
Trial population
Participants will be identified from Mayo Clinic and Mayo Clinic Health System clinical populations, including individuals actively followed for systemic mastocytosis, and may be approached during routine clinical visits, through electronic health record review, by telephone, text message, electronic health record (EHR) portal message, or through participant-initiated contact via the study website.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
25 Participants
are grouped into 1 trial groupGroup A: Indolent Systemic Mastocytosis Cohort
Trial outcomes
Primary outcomes
1
Participant Completion Rate at 12 Weeks
Proportion of enrolled participants who remain in the study and complete the 12 weeks of sample and data collection.
Time frame
12 weeksSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: