Predicting of Frailty
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65+
Sponsorali ihsan uysal
About this trial
This study aims to evaluate the frailty status of elderly patients undergoing surgery for hip fractures (femur trochanteric fractures). Since frailty is a critical factor in surgical outcomes and recovery, researchers want to find simple, fast, and objective ways to measure it. This study will investigate muscle thickness measured by ultrasound, handgrip strength measured by a dynamometer, and routine blood test values can accurately predict a patient's frailty level. If these objective methods are proven effective, it will help anesthesia and surgical teams manage the perioperative process more safely for high-risk elderly patients
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients aged 65 years and older.
Confirmed diagnosis of trochanteric femur fracture.
Planned for orthopedic surgery under general or regional anesthesia.
Ability to provide written informed consent (either by the patient or a legal representative).
Disqualifiers
Patients with advanced dementia or severe cognitive impairment who cannot cooperate with the handgrip strength test or Fried criteria questionnaire.
Patients with terminal-stage diseases or those under palliative care.
History of neuromuscular diseases or severe muscle-wasting conditions that affect the lower limbs (e.g., advanced muscular dystrophy).
Patients with active infections or skin lesions at the site of ultrasound measurement (rectus femoris area).
Trial population
The study population consists of geriatric patients aged 65 years and older who have been hospitalized at the Orthopedics and Traumatology department of Mugla Sitki Kocman University Training and Research Hospital with a diagnosis of trochanteric femur fracture. This population includes patients scheduled for elective or semi-urgent orthopedic surgery who are capable of undergoing preoperative clinical and ultrasonographic assessments.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Clinical and Functional Assessment
Other interventionAssessment of frailty status using the Clinical Frailty Scale and measurement of handgrip strength using a hand dynamometer (measured in kilograms). Ultrasonographic measurement of the rectus femoris muscle thickness (mm) and femur-skin distance (mm) conducted one day before surgery.
Rectus femoris thickness measurement
Other interventionBy using ultrasound linear prob the thickness of rectus femoris muscle will be measured
Treatment groups
100 Participants
are divided into 1 treatment groupGroup A: Elderly Hip Fracture Patients2 interventions
Trial outcomes
Primary outcomes
1
Correlation between Rectus Femoris Muscle Thickness and Frailty Score
Evaluation of the relationship between clinical frailty status (measured by the Clinical Frailty Scale) and objective muscle mass (measured as rectus femoris thickness in millimeters via ultrasonography). Over 5 point indicate frailty.
Time frame
Preoperative (within 24 hours before surgery)Secondary outcomes
1
Predictive Value of Handgrip Strength for Frailty
Assessment of handgrip strength using a hand dynamometer to evaluate its correlation with the Frailty Score.
Time frame
Preoperative2
Correlation of Laboratory Biomarkers with Frailty Status
Evaluation of the relationship between frailty and preoperative blood levels of Albumin, C-Reactive Protein (CRP), Glomerular Filtration Rate (GFR)
Time frame
1 day before operation3
Hematological Indicators of Frailty
Analysis of Hemoglobin levels and Neutrophil-to-Lymphocyte Ratio (NLR) in relation to the patient's frailty score.
Time frame
1 day before operationSponsors and contacts
Click on the lead sponsor to view all of their trials.
ali ihsan uysal
Lead sponsor
Muğla Sıtkı Koçman University
Sponsor institution
Source ClinicalTrials.gov
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