Prediction of Outcome by Echocardiography in Left Bundle Branch Block

ConditionLeft Bundle-Branch Block

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18-100

SponsorUniversity Hospital of North Norway

About this trial

Patients with left bundle branch block have an increased risk for the development of heart-failure and death. However, risk factors for unfavorable outcomes are still poorly defined. This study aims to identify echocardiographic parameters and ECG characteristics by machine learning in order to develop individual risk assessment

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

QRS complex >130 ms and R-wave duration in

V6 >70 ms

ventricular pacing>50%

Previously implanted cardiac resynchronisation therapy (CRT)

Disqualifiers

Typical right bundle branch block.

No ability to give informed consent,

non-cardiovascular co-mobidities with reduced life-expectancy < 1 year

patients with complex congenital heart disease.

Trial population

Patients will be recruited based on epidemiological studies from Tromsø, where LBBB or ventricular pacing has been identified. Further in-hospital patients and patients from the out-patient clinics will be recruited due to ECG assessment

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

Cardiovascular death

Timepoint (day) of death and its cause

Time frame

15 years

Death of any cause

Timepoint (day) of death and its cause

Time frame

15 years

Secondary outcomes

Hospital admission due to heart-failure

Time point of hospital admission and main-diagnosis

Time frame

15 years

Other outcomes

Remodelling

Increase or decrease of ventricular volume in ml

Time frame

5 years

Cardiac function

Increase or decrease of ejection fraction in %

Time frame

5 years

Heart failure

Increase or decrease of heart failure by proBNP and NYHA class

Time frame

5 years

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University Hospital of North Norway

Lead sponsor

Oslo University Hospital

Collaborator

University of Bergen

Collaborator

Norwegian University of Science and Technology

Collaborator

University of Tromso

Collaborator

KU Leuven

Collaborator

Source ClinicalTrials.gov

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