Prediction of Outcome of Non Invasive Ventilation COPD Patients by Assessment of Diaphragmatic Performance

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age40-90
SponsorAssiut University

About this trial

Transthoracic ultrasonographic assessment of the diaphragmatic performance as a predictor for the outcome of NIV in critically ill COPD patients with acute exacerbation.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

One Hundred fifty five critically ill COPD patients admitted to respiratory intensive care unit

Diagnosis of COPD and COPD exacerbation is fulfilled according to GOLD 2022 criteria

Age>40years

Disqualifiers

Age ˂ 40 years.

Refusal to participate in the study.

Patients with morbid obesity (BMI>40).

Absolute indication for intubation like coma ,hemodynamic instability, or life threatening arrhythmia.

Trial population

COPD patients admitted to respiratory intensive care unit with acute exacerbation

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • transthoracic ultrasound

    Other intervention

    The following parameters will be assessed by TUS: Diaphragmatic copulae position and mobility (inspiratory time, excursion, diaphragmatic thickening fraction TF , excursion time E-T index )

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

ultrasonographic assessement of COPD patients

To assess the diaphragmatic performance by transthoracic ultrasound in critically ill COPD patients with acute exacerbation

Time frame
Baseline

Secondary outcomes

1

Time saving

To estimate: * In hospital mortality. * Length of ICU stay. * Length of hospital stay.

Time frame
Baseline

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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