This study looks at people with Alzheimer's disease to find out which factors are linked to their initial score on the Mini-Mental State Examination (MMSE) and which factors may predict a fast decline in their score over 12 months. Researchers will review medical records from patients seen at the Memory Clinic of Gonesse Hospital and analyze information such as age, education, medical history, nutrition, mood, and caregiver burden. The goal is to better understand what influences early cognitive performance and how quickly it changes, to help improve patient care and planning.
Confirmed diagnosis of Alzheimer's disease according to NIAA 2018 or IWG 2021 criteria
At least two MMSE evaluations spaced 12 months apart
Follow-up at the Memory Clinic of CH Gonesse
Presence of other neurodegenerative diseases (e.g., Frontotemporal Dementia, Multiple System Atrophy, Vascular Dementia, LATE)
Patient has moved out of the study area (outside the CH Gonesse territory)
The study population consists of all patients who attended the Memory Clinic at CH Gonesse between July 2023 and July 2025. From this group, participants will be selected if they have a confirmed diagnosis of Alzheimer's disease (based on NIAA 2018 or IWG 2021 criteria) and have undergone at least two MMSE assessments spaced 12 months apart. Data will be extracted from medical records and registries within this hospital setting.
Cohort
Retrospective
Not listed
Change in MMSE Score Over 12 Months - measured as either a decrease of ≥3 points on the Mini-Mental State Examination [MeSH] or patient institutionalization within 12 months.
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