Predictors of Failed Thrombolysis in Acute Myocardial Infarction
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorOslo University Hospital
About this trial
The purpose of this observational study is to assess why thrombolytic treatment with tissue-plasminogen activator (t-PA) fails in patients with acute ST-segment elevation myocardial infarction (STEMI). The study will include 200 STEMI patients at the time of arrival at Oslo University Hospital Ullevål after receiving prehospital thrombolysis. A blood sample will be taken immediately for the study of factors related to coagulation, fibrinolysis and inflammation. Levels of the biomarkers will be compared between patients with successful and failed thrombolysis.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
None
Trial population
The study will include all STEM patients who have received prehospital thrombolysis before hospital admission.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Successfull thrombolysis
Diagnostic testBiomarker levels will be compared between patients with successful and failed thrombolysis.
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
Failed thrombolysis
Persistent chest pain and/or \< 50 % ST segment resolution
Time frame
Decided immediately after hospital admission.Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov