Predictors of ICU Admission and In-Hospital Mortality in Hospitalized Patients With Lupus Nephritis: The Prognostic Value of Neutrophil-to-Lymphocyte Ratio and C Reactive Protein to Serum Albumin Ratio

ConditionLupus Nephritis (LN)

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18-70

SponsorKhaled Samir Malak Nashed

About this trial

To identify clinical and laboratory predictors of ICU admission and in-hospital mortality among hospitalized adults with lupus nephritis by evaluating the prognostic performance of NLR and CAR, comparing them with CRP and albumin using ROC analysis, determining optimal cutoff values, and identifying independent predictors through multivariable logistic regression

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age ≥18 years.

Diagnosis of systemic lupus erythematosus according to the 2019 EULAR/ACR Classification Criteria.

Biopsy-proven lupus nephritis or clinically diagnosed lupus nephritis according to the treating nephrologist based on clinical, laboratory and immunological findings.

Hospitalization because of active lupus nephritis or complications related to lupus nephritis.

Disqualifiers

Age below 18 years.

Previous kidney transplantation.

Maintenance dialysis for more than three months before hospital admission.

Active malignancy.

Trial population

Hospitalized adult patients with Lupus Nephritis.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

Number of participants of ICU admission or In-hospital mortality.

Time frame

8 weeks

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Khaled Samir Malak Nashed

Lead sponsor

Assiut University

Sponsor institution