Predictors of Outcomes in Pulmonary Hypertension of the Newborn
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 28
SponsorAssiut University
About this trial
This prospective cohort study aims to identify the clinical, laboratory, and echocardiographic predictors of outcomes among neonates diagnosed with persistent pulmonary hypertension of the newborn at Assiut University Children Hospital.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
- Neonates (term and preterm) admitted to the NICU
Clinical and echocardiographic evidence of pulmonary hypertension
Written informed consent from parents or legal guardians
Disqualifiers
- Major structural cyanotic congenital heart disease
Lethal congenital anomalies or chromosomal abnormalities incompatible with survival
Trial population
Term and preterm neonates admitted to the Neonatal Intensive Care Unit of Assiut University Children Hospital with clinical and echocardiographic evidence of persistent pulmonary hypertension.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
60 Participants
are grouped into 1 trial groupGroup A: Single cohort: Neonates with PPHN
Trial outcomes
Primary outcomes
1
In-hospital mortality
Proportion of neonates with persistent pulmonary hypertension who die before hospital discharge.
Time frame
Up to 30 daysSecondary outcomes
1
Duration of mechanical ventilation
Total number of days of invasive mechanical ventilation.
Time frame
Up to 30 days2
Duration of oxygen therapy
Total number of days requiring supplemental oxygen.
Time frame
Up to 30 days3
Use of sildenafil
Proportion of neonates who receive sildenafil therapy.
Time frame
Up to 30 days4
Use of inotropes
Proportion of neonates who receive inotropic support
Time frame
Up to 30 daysLocations
Sponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: