Predictors of Post-clamping Neurologic Deficits During Carotid Endarterectomy With Regional Anesthesia

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-100
SponsorUniversidade do Porto

About this trial

Patients undergoing carotid endarterectomy may suffer from neurologic deficits (ND) during the carotid cross-clamping due to cerebral hypoperfusion. An associated risk of postoperative stroke incidence is also well established.

The aim of this study is to evaluate the predictive factors associated with ND during CEA performed with RA. The perioperative implications of the ND were also evaluated.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

carotid endarterectomy under regional anesthesia

Postclamping carotid deficit

Disqualifiers

carotid stenting

Trial population

Post-clamping deficits were defined as any persistent alteration at neurologic examination during the CACC and resistant to hemodynamic adjustment

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

  • carotid endarterectomy

    Procedure/Surgery

    shunt

Treatment groups

206 Participants
are divided into 2 treatment groups
Group A: Neurologic deficit1 intervention
Group B: control1 intervention

Trial outcomes

Primary outcomes

1

Stroke

An episode of neurological dysfunction caused by focal cerebral, spinal, or retinal infarction.

Time frame
up to 5 years

Secondary outcomes

1

Clavien-Dindo Classification >3

Postoperative event life threatining and requiring surgical, endoscopic or radiological intervention

Time frame
30 days

Other outcomes

1

Major adverse cardiosvascular and cerebrovascular events

AMI, Stroke, AHF hospitalization, MALE, MACE, All-cause mortality

Time frame
up to 5 years

Sponsors and contacts

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