Health TrialsbyHealthPanel

Pregnancy and Developmental Outcomes After Transfer of Reportedly Aneuploid or Mosaic Embryos

ConditionsAneuploidyMosaicismPregnancy Outcome
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-55
SponsorStanford University

About this trial

To determine how often embryos reported to be abnormal by preimplantation genetic testing result in liveborn infants. To evaluate whether the pregnancies that result from these embryos are higher risk for complications and whether the resulting babies have higher risk for health or developmental issues in the first five years after birth.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Available aneuploid or mosaic embryos

No other acceptable embryos available

Willing to travel to Stanford for treatment

English language fluency

Disqualifiers

Use of international donor eggs or sperm not tested according to FDA guidelines.

Living outside the United States

Embryos with Triploidy are not eligible for transfer in this protocol

Trial design

Design model

Parallel

Treatments tested in this trial

  • Non-euploid embryo transfer

    Other intervention

    Other than choice of embryo for transfer, all other medical interventions will be standard of care protocols

  • Euploid Transfer

    Other intervention

    Standard of Care Protocol

Treatment groups

300 Participants
are divided into 2 treatment groups
Group A: Non-euploid TransferExperimental treatment 1 intervention
Group B: Euploid TransferActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Pregnancy Rate

Number participants who undergo embryo transfers that lead to a positive pregnancy test

Time frame
3 years

Secondary outcomes

1

Live birth rate

Number participants who conceive after embryo transfer and have a live birth.

Time frame
4 years
2

Obstetric complications

Number of participants who have a maternal of fetal complication after embryo transfer

Time frame
4 years
3

Pediatric Development

Number of newborns and children who have abnormal pediatric development at 3 months, 2 years and 5 years following birth

Time frame
7 years 3 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Stanford University

Lead sponsor

Source ClinicalTrials.gov
Apply now