Prehab Prior to Stem Cell Transplantation in Multiple Myeloma
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Alberta
About this trial
The primary purpose of this study is to see if individuals with Multiple Myeloma are able and interested in taking part in a tailored exercise program while undergoing their chemotherapy prior to a stem cell transplant. We also hope to learn if this type of program, along with a flexible delivery format (in-person and virtual), helps in maintaining or improving physical fitness, muscle mass and strength, and quality of life during chemotherapy.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Have a diagnosis of Multiple Myeloma
Be transplant eligible
Be undergoing chemotherapy prior to, or following an autologous stem cell transplant as part of their cancer treatment; or transplant ineligible.
Be an Alberta resident
Disqualifiers
Their disease status/comorbidities preclude exercise testing or participation
They are unable to commit to the 10-week exercise program and/or testing sessions at the Cancer Rehabilitation Clinic at the University of Alberta
They do not have regular access to the internet and/or an electronic device in the home.
Trial design
Design model
Parallel
Treatments tested in this trial
Supported Exercise
BehavioralParticipants will take part in a prehabilitation exercise program prior to undergoing a stem cell transplant.
Standard Care
BehavioralParticipants will receive standard care
Treatment groups
30 Participants
are divided into 2 treatment groupsGroup A: Standard CareActive comparator 1 intervention
Group B: Supported Exercise GroupExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Study completion rate
The percentage of participants who complete the study, including the intervention and follow-up assessment
Time frame
10-weeksSecondary outcomes
1
Recruitment rate
The percentage of participants who are eligible and consent to participate in the study.
Time frame
18 months2
Attendance rate
The percentage of group and individual exercise sessions completed over the 10 weeks.
Time frame
18 months3
Edmonton Symptom Assessment System
Tool to assess 11 symptoms related to cancer: higher scores reflect worse symptom burden
Time frame
10 weeks4
Functional Assessment of Cancer Therapy Multiple Myeloma
Health-related quality of life questionnaire: higher scores reflect better quality of life
Time frame
10 weeksSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov